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WHO global research priorities for antimicrobial resistance in human health

Abstract

The WHO research agenda for antimicrobial resistance (AMR) in human health has identified 40 research priorities to be addressed by the year 2030. These priorities focus on bacterial and fungal pathogens of crucial importance in addressing AMR, including drug-resistant pathogens causing tuberculosis. These research priorities encompass the entire people-centred journey, covering prevention, diagnosis, and treatment of antimicrobial-resistant infections, in addition to addressing the overarching knowledge gaps in AMR epidemiology, burden and drivers, policies and regulations, and awareness and education. The research priorities were identified through a multistage process, starting with a comprehensive scoping review of knowledge gaps, with expert inputs gathered through a survey and open call. The priority setting involved a rigorous modified Child Health and Nutrition Research Initiative approach, ensuring global representation and applicability of the findings. The ultimate goal of this research agenda is to encourage research and investment in the generation of evidence to better understand AMR dynamics and facilitate policy translation for reducing the burden and consequences of AMR.

More information

Type
Journal Article
Author
Bertagnolio S
Dobreva Z
Centner CM
Olaru ID
Donà D
Burzo S
Huttner BD
Chaillon A
Gebreselassie N
Wi T
Hasso-Agopsowicz M
Allegranzi B
Sati H
Ivanovska V
Kothari KU
Balkhy HH
Cassini A
Hamers RL
Weezenbeek KV
Aanensen D
Alanio A
Alastruey-Izquierdo A
Alemayehu T
Al-Hasan M
Allegaert K
Al-Maani AS
Al-Salman J
Alshukairi AN
Amir A
Applegate T
Araj GF
Villalobos MA
Årdal C
Ashiru-Oredope D
Ashley EA
Babin F
Bachmann LH
Bachmann T
Baker KS
Balasegaram M
Bamford C
Baquero F
Barcelona LI
Bassat Q
Bassetti M
Basu S
Beardsley J
Vásquez GB
Berkley JA
Bhatnagar AK
Bielicki J
Bines J
Bongomin F
Bonomo RA
Bradley JS
Bradshaw C
Brett A
Brink A
Brown C
Brown J
Buising K
Carson C
Carvalho AC
Castagnola E
Cavaleri M
Cecchini M
Chabala C
Chaisson RE
Chakrabarti A
Chandler C
Chandy SJ
Charani E
Chen L
Chiara F
Chowdhary A
Chua A
Chuki P
Chun DR
Churchyard G
Cirillo D
Clack L
Coffin SE
Cohn J
Cole M
Conly J
Cooper B
Corso A
Cosgrove SE
Cox H
Daley CL
Darboe S
Darton T
Davies G
de Egea V
Dedeić-Ljubović A
Deeves M
Denkinger C
Dillon JR
Dramowski A
Eley B
Roberta Esposito SM
Essack SY
Farida H
Farooqi J
Feasey N
Ferreyra C
Fifer H
Finlayson H
Frick M
Gales AC
Galli L
Gandra S
Gerber JS
Giske C
Gordon B
Govender N
Guessennd N
Guindo I
Gurbanova E
Gwee A
Hagen F
Harbarth S
Haze J
Heim J
Hendriksen R
Heyderman RS
Holt KE
Hönigl M
Hook EW
Hope W
Hopkins H
Hughes G
Ismail G
Issack MI
Jacobs J
Jasovský D
Jehan F
Pearson AJ
Jones M
Joshi MP
Kapil A
Kariuki S
Karkey A
Kearns GL
Keddy KH
Khanna N
Kitamura A
Kolho K
Kontoyiannis DP
Kotwani A
Kozlov RS
Kranzer K
Kularatne R
Lahra MM
Langford BJ
Laniado-Laborin R
Larsson J
Lass-Flörl C
Le Doare K
Lee H
Lessa F
Levin AS
Limmathurotsakul D
Lincopan N
Lo Vecchio A
Lodha R
Loeb M
Longtin Y
Lye DC
Mahmud AM
Manaia C
Manderson L
Mareković I
Marimuthu K
Martin I
Mashe T
Mei Z
Meis JF
Lyra Tavares De Melo FA
Mendelson M
Miranda AE
Moore D
Morel C
Moremi N
Moro ML
Moussy F
Mshana S
Mueller A
Ndow FJ
Nicol M
Nunn A
Obaro S
Obiero CW
Okeke IN
Okomo U
Okwor TJ
Oladele R
Omulo S
Ondoa P
Ortellado de Canese JM
Ostrosky-Zeichner L
Padoveze MC
Pai M
Park B
Parkhill J
Parry CM
Peeling R
Sobreira Vieira Peixe LM
Perovic O
Pettigrew MM
Principi N
Pulcini C
Puspandari N
Rawson T
Reddy DL
Reddy K
Redner P
Rodríguez Tudela JL
Rodríguez-Baño J
Van Katwyk SR
Roilides E
Rollier C
Rollock L
Ronat J
Ruppe E
Sadarangani M
Salisbury D
Salou M
Samison LH
Sanguinetti M
Sartelli M
Schellack N
Schouten J
Schwaber MJ
Seni J
Senok A
Shafer WM
Shakoor S
Sheppard D
Shin J
Sia S
Sievert D
Singh I
Singla R
Skov RL
Soge OO
Sprute R
Srinivasan A
Srinivasan S
Sundsfjord A
Tacconelli E
Tahseen S
Tangcharoensathien V
Tängdén T
Thursky K
Thwaites G
Tigulini de Souza Peral R
Tong D
Tootla HD
Tsioutis C
Turner KM
Turner P
Omar SV
van de Sande WW
van den Hof S
van Doorn R
Veeraraghavan B
Verweij P
Wahyuningsih R
Wang H
Warris A
Weinstock H
Wesangula E
Whiley D
White PJ
Williams P
Xiao Y
Moscoso MY
Yang HL
Yoshida S
Yu Y
Żabicka D
Zignol M

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