Missed, but Momentous: A Comprehensive Review of Neglected Tropical Skin Diseases in Southern India and their Global Impact

Neglected tropical skin diseases (NTDs) are a group of overlooked afflictions that affect marginalized populations and hinder the advancement of global health in the right direction. India, a significant hotspot, suffers immensely from these diseases, with South India providing a conducive environment for the spread and persistence of causative pathogens, leading to disastrous local and, ultimately, global consequences. Diseases such as leprosy, subcutaneous and deep mycoses, leishmaniasis, and filariasis are endemic to this region. Understanding the factors that make South India a hub for these diseases is crucial in getting to the heart of the problem. Despite notable progress, NTDs persist, sustained by the factors such as low socio-economic status, congested living conditions, and malnutrition. The challenges in NTD management encompass delayed diagnosis and resistance. However, initiatives such as the Kigali Declaration advocate for global collaboration, stressing prevention, treatment, and research. A thorough literature search was undertaken, concentrating on peer-reviewed articles and case reports published in English within the past decade. This systematic review aims to probe into the intricate facets of NTDs in South India, delving into each dermatological NTD in detail, spotlighting their essence, prevalence, socio-economic reverberations, hurdles, and the necessity for collective action. By prioritizing NTD control in South India, we can collectively alleviate local suffering and contribute to global health security and equity, charting a course toward a healthier, more resilient world.