TY - JOUR
KW - Parasitology
KW - Infectious Diseases
KW - General Medicine
KW - praziquantel (PZQ)
AU - Enabulele EE
AU - Platt RN
AU - Adeyemi E
AU - Agbosua E
AU - Aisien MS
AU - Ajakaye OG
AU - Ali MU
AU - Amaechi EC
AU - Atalabi TE
AU - Auta T
AU - Awosolu OB
AU - Dagona AG
AU - Edo-Taiwo O
AU - Ejikeugwu CE
AU - Igbeneghu C
AU - Njom VS
AU - Orji MN
AU - Oyinloye FO
AU - Ozemoka HJ
AU - Ugah UI
AU - Anderson TJ
AB - Schistosomiasis control efforts in Nigeria received a boost in 2016 when Merck Group made the largest single donation of praziquantel to an African country. We examined urine samples from 2,023 school age children from 15 locations in 10 states and an Internally Displaced Person's (IDP) camp in Nigeria. We recorded an overall Schistosoma haematobium prevalence of 10.4% in the 10 states that ranged between 6 – 37%, while prevalence in the IDP camp was 2.9%. The highest infection prevalence (37%) recorded was from the population in Wasai Dam area in Minjibir (Kano State), while five locations had no positive urine samples. We observed heavy intensity of infection (≥ 50 eggs/10 ml urine) in 87.9% of infected samples and co-occurrence of the eggs of S. haematobium and S. mansoni in urine for two participants. The overall prevalence we recorded is slightly above the national average (9.5%) reported in 2015. Our findings indicate that despite the ongoing administration of praziquantel in Nigeria, urogenital schistosomiasis is still prevalent with heavy intensity of infection. Large-scale epidemiological monitoring is required to monitor the efficacy of schistosomiasis control in Nigeria.
BT - Acta Tropica
DO - 10.1016/j.actatropica.2021.105916
LA - eng
N2 - Schistosomiasis control efforts in Nigeria received a boost in 2016 when Merck Group made the largest single donation of praziquantel to an African country. We examined urine samples from 2,023 school age children from 15 locations in 10 states and an Internally Displaced Person's (IDP) camp in Nigeria. We recorded an overall Schistosoma haematobium prevalence of 10.4% in the 10 states that ranged between 6 – 37%, while prevalence in the IDP camp was 2.9%. The highest infection prevalence (37%) recorded was from the population in Wasai Dam area in Minjibir (Kano State), while five locations had no positive urine samples. We observed heavy intensity of infection (≥ 50 eggs/10 ml urine) in 87.9% of infected samples and co-occurrence of the eggs of S. haematobium and S. mansoni in urine for two participants. The overall prevalence we recorded is slightly above the national average (9.5%) reported in 2015. Our findings indicate that despite the ongoing administration of praziquantel in Nigeria, urogenital schistosomiasis is still prevalent with heavy intensity of infection. Large-scale epidemiological monitoring is required to monitor the efficacy of schistosomiasis control in Nigeria.
PB - Elsevier BV
PY - 2021
EP - 105916
T2 - Acta Tropica
TI - Urogenital schistosomiasis in Nigeria post receipt of the largest single praziquantel donation in Africa
VL - 219
SN - 0001-706X
ER -