Recent mathematical and statistical modeling of leprosy incidence data provides estimates of the current undiagnosed population and projections of diagnosed cases, as well as ongoing transmission. Furthermore, modeling studies have been used to evaluate the effectiveness of proposed intervention strategies, such as postleprosy exposure prophylaxis and novel diagnostics, relative to current approaches. Such modeling studies have revealed both a slow decline of new cases and a substantial pool of undiagnosed infections. These findings highlight the need for active case detection, particularly targeting leprosy foci, as well as for continued research into innovative accurate, rapid, and cost-effective diagnostics. As leprosy incidence continues to decline, targeted active case detection primarily in foci and connected areas will likely become increasingly important.
BT - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America C1 -http://www.ncbi.nlm.nih.gov/pubmed/29860289?dopt=Abstract
DO - 10.1093/cid/ciy005 IS - suppl_4 J2 - Clin. Infect. Dis. LA - eng N2 -Recent mathematical and statistical modeling of leprosy incidence data provides estimates of the current undiagnosed population and projections of diagnosed cases, as well as ongoing transmission. Furthermore, modeling studies have been used to evaluate the effectiveness of proposed intervention strategies, such as postleprosy exposure prophylaxis and novel diagnostics, relative to current approaches. Such modeling studies have revealed both a slow decline of new cases and a substantial pool of undiagnosed infections. These findings highlight the need for active case detection, particularly targeting leprosy foci, as well as for continued research into innovative accurate, rapid, and cost-effective diagnostics. As leprosy incidence continues to decline, targeted active case detection primarily in foci and connected areas will likely become increasingly important.
PY - 2018 SP - S281 EP - S285 T2 - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America TI - Policy lessons from quantitative modeling of leprosy. UR - https://academic.oup.com/cid/article/66/suppl_4/S281/5020606 VL - 66 SN - 1537-6591 ER -