01983nas a2200325   4500000000100000008004100001260001200042653001300054653002700067653001700094653004100111653003900152653002800191653003300219653001700252653001300269653001400282100001200296700001600308700001200324700001300336700001600349700002000365245008600385856006700471300000900538490000700547520108900554022001401643       2024                            d  bMDPI AG10aVirology10aMicrobiology (medical)10aMicrobiology10aFemale genital schistosomiasis (FGS)10aNeglected tropical diseases (NTDs)10aSchistosoma haematobium10aschistosomiasis in pregnancy10aschisto-IRIS10aimmunity10ascreening1 aRossi B1 aPrevitali L1 aSalvi M1 aGerami R1 aTomasoni LR1 aQuiros-Roldan E00aFemale Genital Schistosomiasis: A Neglected among the Neglected Tropical Diseases  uhttps://www.mdpi.com/2076-2607/12/3/458/pdf?version=1709017254  a1-150 v123 a<p>Schistosomiasis is a neglected parasitic disease linked to water, posing a global public health concern with a significant burden in sub-Saharan Africa. It is transmitted by Schistosoma spp., causing both acute and chronic effects affecting the urogenital or the hepato-intestinal system. Through granuloma formation, chronic schistosomiasis weakens host immunity, heightening susceptibility to coinfections. Notably, female genital schistosomiasis (FGS), a disregarded gynecological condition, adversely affects girls’ and women’s reproductive health and increases vulnerability to HIV. This review explores the intricate interplay between schistosomiasis and HIV, considering their geographical overlap. We delve into the clinical features of this coinfection, underlying mutual influences on transmission, diagnostic challenges, and therapeutic approaches. Understanding the dynamics of FGS and HIV coinfection is pivotal for integrated healthcare strategies in regions with co-endemicity, aiming to mitigate the impact of the two infections on vulnerable populations.</p>
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