02277nas a2200313 4500000000100000008004100001260001200042100001200054700001200066700001300078700001300091700001200104700001400116700001700130700001200147700001100159700001300170700001100183700001000194700001500204700001200219700002000231245009300251856009900344300000900443490000700452520149000459022001401949 2023 d c11/20231 aEkeke N1 aIyama F1 aChukwu J1 aAsiedu K1 aMarks M1 aOmotowo B1 aAgwu-Umahi O1 aNvene V1 aPaul S1 aNwafor C1 aMeka A1 aEze C1 aEzeakile O1 aNjoku M1 aMurphy-Okpala N00aIs there still yaws in Nigeria? Active case search in endemic areas of southern Nigeria. uhttps://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011753&type=printable a1-100 v173 a

Background: Yaws is a disease caused by the bacteria Treponema pallidum subspecies pertenue, which is most commonly seen among children below 15 years. In the twentieth century yaws was endemic in Nigeria but eradication strategies markedly reduced the disease burden. Currently there is minimal data on the ongoing transmission of yaws in Nigeria, despite reports of confirmed yaws cases in neighbouring West African countries.

Methods: We conducted both community and school-based active yaws case search among school-aged children in southeast Nigeria. Children were screened by trained community volunteers. Suspected yaws cases were clinically reviewed and tested using rapid diagnostic serological tests.

Results: Between February and May 2021, up to 28 trained community volunteers screened a total of 105,015 school children for yaws. Overall, 7,706 children with various skin lesions were identified. Eight (8) suspected cases of yaws were reported, reviewed and screened, but none was confirmed using rapid diagnostic tests. The four most common skin conditions identified were scabies (39%), papular urticaria (29%), tinea corporis (14%) and tinea capitis (12%).

Conclusions: No case of yaws was confirmed in this large population of children in south-east Nigeria. Continuous community awareness and yaws case finding activities have been recommended across Nigeria.

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