01919nas a2200229 4500000000100000008004100001260002200042653004900064653005700113653005400170653003100224100001300255700001600268700002100284700001600305245016300321856007100484300000800555490000800563520109300571022002501664 2023 d bThe Royal Society10aGeneral Agricultural and Biological Sciences10aGeneral Biochemistry, Genetics and Molecular Biology10aLondon Declaration on Neglected Tropical Diseases10achallenges & opportunities1 aForbes K1 aBasáñez M1 aHollingsworth TD1 aAnderson RM00aIntroduction to the special issue: challenges and opportunities in the fight against neglected tropical diseases: a decade from the London Declaration on NTDs uhttps://royalsocietypublishing.org/doi/epdf/10.1098/rstb.2022.0272 a1-80 v3783 a

Twenty neglected tropical diseases (NTDs) are currently prioritised by the World Health Organization for eradication, elimination as a public health problem, elimination of transmission or control by 2030. This issue celebrates progress made since the 2012 London Declaration on NTDs and discusses challenges currently faced to achieve these goals. It comprises 14 contributions spanning NTDs tackled by intensified disease management to those addressed by preventive chemotherapy. Although COVID-19 negatively affected NTD programmes, it also served to spur new multisectoral approaches to strengthen school-based health systems. The issue highlights the needs to improve impact survey design, evaluate new diagnostics, understand the consequences of heterogeneous prevalence and human movement, the potential impact of alternative treatment strategies and the importance of zoonotic transmission.

This article is part of the theme issue ‘Challenges and opportunities in the fight against neglected tropical diseases: a decade from the London Declaration on NTDs’.

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