01936nas a2200265   4500000000100000008004100001260003400042653004900076653005700125653002400182100001400206700001300220700001600233700001200249700001600261700001700277700001500294700001700309245014000326856026000466300000800726490000900734520091300743022001401656       2023                            d  bOxford University Press (OUP)10aGeneral Agricultural and Biological Sciences10aGeneral Biochemistry, Genetics and Molecular Biology10aInformation Systems1 aBrochet P1 aMouren J1 aHannouche L1 aLopez F1 aBallester B1 aCunha-Neto E1 aSpinelli L1 aChevillard C00aChagasDB: 80 years of publicly available data on the molecular host response to <i>Trypanosoma cruzi</i> infection in a single database  uhttps://watermark.silverchair.com/baad037.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAuAwggLcBgkqhkiG9w0BBwagggLNMIICyQIBADCCAsIGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM9TCwbt-lQ9x4C0ibAgEQgIICk9jhV3MYmgGftTFerLLoDQy3pa1QfDSd0Ys0Gp6LZcAeODR  a1-50 v20233 a<p>Chagas disease is a parasitical disease caused by Trypanosoma cruzi which affects ∼7 million people worldwide. Per year, ∼10 000 people die from this pathology. Indeed, ∼30% of humans develop severe chronic forms, including cardiac, digestive or neurological disorders, for which there is still no treatment. In order to facilitate research on Chagas disease, a manual curation of all papers corresponding to ‘Chagas disease’ referenced on PubMed has been performed. All deregulated molecules in hosts (all mammals, humans, mice or others) following T. cruzi infection were retrieved and included in a database, named ChagasDB. A website has been developed to make this database accessible to all. In this article, we detail the construction of this database, its contents and how to use it. Database URL <a href="https://chagasdb.tagc.univ-amu.fr/">https://chagasdb.tagc.univ-amu.fr</a></p>
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