02025nas a2200193   4500000000100000008004100001260003400042653002400076653005700100653002100157653001700178100001200195700001000207700001800217245009500235856010400330520137200434022002501806       2023                            d  bOxford University Press (OUP)10aInfectious Diseases10aPublic Health, Environmental and Occupational Health10aGeneral Medicine10aParasitology1 aGuile L1 aLee A1 aGutiérrez JM00aFactors associated with mortality after snakebite envenoming in children: a scoping review  uhttps://academic.oup.com/trstmh/advance-article-pdf/doi/10.1093/trstmh/trad031/50507067/trad031.pdf3 a<p>ABSTRACT</p>

<p>Snakebite envenoming is an important public health issue in many tropical and subtropical countries, where the burden of morbidity and mortality falls particularly on impoverished rural communities. Children are an especially vulnerable group. This scoping review provides an overview of the extent, type and content of peer-reviewed evidence regarding factors associated with mortality in snakebite-envenomed children. A comprehensive literature search of MEDLINE and the Global Index Medicus yielded 623 articles, of which 15 met the criteria for inclusion; 67% of studies were conducted in India, with the remaining studies taking place in Papua New Guinea, Morocco and The Gambia. There was a notable scarcity of eligible studies from sub-Saharan Africa and Latin America despite the high burden of envenoming in these regions. The risk factors for mortality that were identified by the greatest number of studies were younger patient age (n=4), delay in administration of antivenom (n=4) and acute kidney injury (n=3). Identification of poor prognostic factors can assist clinicians in making timely referrals to centres with paediatric critical care capability. Future research must address the lack of studies from key geographical regions so that evidence-based improvements to the care of this vulnerable group can be implemented.</p>
  a0035-9203, 1878-3503