01281nas a2200241   4500000000100000008004100001260001600042653002400058653001700082653001600099653001300115653001000128100001600138700001500154700002000169700001400189245006900203856007000272300001200342490000700354520066400361022001401025       2023                            d  bElsevier BV10aInfectious Diseases10aParasitology10aCoinfection10ahelminth10avirus1 aPetrellis G1 aPiedfort O1 aKatsandegwaza B1 aDewals BG00aParasitic worms affect virus coinfection: a mechanistic overview  uhttps://www.cell.com/action/showPdf?pii=S1471-4922%2823%2900040-5  a358-3720 v393 a<p>Helminths are parasitic worms that coevolve with their host, usually resulting in long-term persistence through modulating host immunity. The multifarious mechanisms altering the immune system induced by helminths have significant implications on the control of coinfecting pathogens such as viruses. Here, we explore the recent literature to highlight the main immune alterations and mechanisms that affect the control of viral coinfection. Insights from these mechanisms are valuable in the understanding of clinical observations in helminth-prevalent areas and in the design of new therapeutic and vaccination strategies to control viral diseases.</p>
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