02612nas a2200373   4500000000100000008004100001260004400042653002400086653001900110653002300129653002100152653001700173100001700190700001400207700001100221700001500232700001700247700001200264700001600276700001300292700001700305700001500322700001400337700001400351700001400365700001600379700001800395700001300413700001400426245012100440856007300561520157900634022002502213       2022                            d  bSpringer Science and Business Media LLC10aInfectious Diseases10aInsect Science10aGeneral Veterinary10aGeneral Medicine10aParasitology1 aCoulibaly YI1 aSangare M1 aDolo H1 aSoumaoro L1 aCoulibaly SY1 aDicko I1 aDiabaté AF1 aDiarra L1 aCoulibaly ME1 aDoumbia SS1 aDiallo AA1 aDembele M1 aKoudou BG1 aBockarie MJ1 aKelly-Hope LA1 aKlion AD1 aNutman TB00aNo evidence of lymphatic filariasis transmission in Bamako urban setting after three mass drug administration rounds  uhttps://link.springer.com/content/pdf/10.1007/s00436-022-07648-8.pdf3 a<p>Lymphatic filariasis (LF) elimination activities started in Mali in 2005 in the most endemic areas and reached countrywide coverage in 2009. In 2004, the district of Bamako was endemic for LF with a prevalence of 1.5%. The current study was designed to determine LF endemicity level in the urban area of Bamako after three rounds of ivermectin and albendazole mass drug administration (MDA). A cross-sectional study was conducted in 2011 in Bamako city, consisting of human prevalence and entomological surveys. Volunteers aged 14&nbsp;years and above were invited to participate and tested for evidence of Wuchereria bancrofti using night time blood thick smear microfilarial count and blood spots for LF antibodies using the SD BIOLINE Oncho/LF IgG4 Biplex rapid test (Ov16/Wb123). Mosquitoes were collected using CDC light and gravid traps and tested using molecular methods. Poolscreen software v2.0 was used to estimate vector transmission potential. Of the 899 volunteers, one (0.11%) was found to be positive for LF using the Oncho/LF IgG4 Biplex rapid test, and none was found to have Wuchereria bancrofti microfilariae. No mosquitoes were found infected among 6174 Culex spp. (85.2%), 16 Anopheles gambiae s.l. (An. gambiae s.l.) (0.2%), 26 Aedes spp. (0.4%), 858 Ceratopogonidae (11.8%) and 170 other insects not identified (2.3%) tested. Our data indicate that there was no active LF transmission in the low prevalence urban district of Bamako after three MDA rounds. These data helped the National LF programme move forward towards the elimination goal.</p>
  a0932-0113, 1432-1955