02531nas a2200241   4500000000100000008004100001260004000042653005700082653001800139100002200157700001200179700001300191700001700204700001300221700002400234700001600258700001500274245019600289856006600485490000700551520170600558022002502264       2022                            d  bInternational Global Health Society10aPublic Health, Environmental and Occupational Health10aHealth Policy1 aMontiel Ishino FA1 aRowan C1 aTalham C1 aVillalobos K1 aPoudel D1 aRajbhandari-Thapa J1 aAmbikile JS1 aWilliams F00aHousehold profiles of neglected tropical disease symptoms among children: A latent class analysis of built-environment features of Tanzanian households using the Demographic and Health Survey  uhttps://jogh.org/wp-content/uploads/2022/09/jogh-12-04067.pdf0 v123 a<p><strong>Background:&nbsp;</strong>While malaria and neglected tropical disease (NTD) morbidity and mortality rates among children &lt;5 years old have decreased through public health efforts in the United Republic of Tanzania, associations between household environments and disease outcomes are relatively unknown.</p>

<p><strong>Methods:&nbsp;</strong>We conducted latent class analysis (LCA) on 2015-2016 Tanzania Demographic Health Survey data from mothers with children &lt;5 years old (N = 10 233) to identify NTD household risk profiles. The outcome of child NTD was assessed by mothers' reports of recent diarrhoea, cough, treatment for enteric parasites, and fever symptoms. Household-built environment indicators included urban/rural designation, electricity access, water source, cooking fuel, flooring, wall, and roofing materials. External environmental covariates were considered to further differentiate profiles.</p>

<p><strong>Results:&nbsp;</strong>Five profiles were identified in the sample: rural finished walls households (40.2%) with the lowest NTD risk; rural rudimentary households (20.9%) with intermediate-low NTD risk; finished material households (22.5%) with intermediate NTD risk; urban households (14.4%) with intermediate-high NTD risk and high likelihood of enteric parasites; rural finished roof/walls households (2.1%) with the highest overall NTD risk.</p>

<p><strong>Conclusions:&nbsp;</strong>This study is among the first to use LCA to examine household environment characteristics to assess child NTD risk in Tanzania. This paper serves as a framework for community-level rapid NTD risk assessment for targeted health promotion interventions.</p>
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