01437nas a2200217   4500000000100000008004100001260003700042653002000079653003100099653001700130653000900147100001300156700001700169700001400186700001500200700001400215245011500229490000600344520085500350022001401205       2020                            d  beLife Sciences Publications, Ltd10aschistosomiasis10aSchistosomiasis haematobia10aTransmission10aWASH1 aMogeni P1 aVandormael A1 aCuadros D1 aAppleton C1 aTanser FC00aImpact of community piped water coverage on re-infection with urogenital schistosomiasis in rural South Africa0 v93 a<jats:p>Previously, we demonstrated that high coverage of piped water in the seven years preceding a parasitological survey was strongly predictive of Schistosomiasis haematobium infection in a nested cohort of 1,976 primary school children [1]. Here, we report on the prospective follow up of infected members of this nested cohort (N=333) for two successive rounds following treatment. Using a negative binomial regression fitted to egg count data, we found that every percentage point increase in piped water coverage was associated with 4.4% decline in intensity of re-infection (incidence rate ratio = 0.96, 95%CI: 0.93-0.98, P= 0.002) among the treated children. We therefore provide further compelling evidence in support of the scaleup of piped water as an effective control strategy against Schistosomiasis haematobium transmission.</jats:p>  a2050-084X