02017nas a2200337 4500000000100000008004100001653003900042653001600081653001100097653001700108653000900125653003400134653001800168653001800186653001900204653001900223653002200242653000900264653002600273653002100299653002600320653001200346653001300358100001100371700001900382700001400401700001200415245011300427520112500540022001401665 2017 d10aNeglected tropical diseases (NTDs)10aChikungunya10aDengue10aYellow Fever10aZika10aHantavirus pulmonary syndrome10aLeptospirosis10aLeishmaniasis10aChagas disease10aClimate change10aDisease emergence10aEIDs10aEnvironmental drivers10aLandscape change10aVector-borne diseases10aWeather10aZoonoses1 aNava A1 aShimabukuro JS1 aChmura AA1 aLuz SLB00aThe impact of global environmental changes on infectious disease emergence with a focus on risks for Brazil.3 a

Environmental changes have a huge impact on the emergence and reemergence of certain infectious diseases, mostly in countries with high biodiversity and serious unresolved environmental, social, and economic issues. This article summarizes the most important findings with special attention to Brazil and diseases of present public health importance in the country such as Chikungunya, dengue fever, yellow fever, Zika, hantavirus pulmonary syndrome, leptospirosis, leishmaniasis, and Chagas disease. An extensive literature review revealed a relationship between infectious diseases outbreaks and climate change events (El Niño, La Niña, heatwaves, droughts, floods, increased temperature, higher rainfall, and others) or environmental changes (habitat fragmentation, deforestation, urbanization, bushmeat consumption, and others). To avoid or control outbreaks, integrated surveillance systems and effective outreach programs are essential. Due to strong global and local influence on emergence of infectious diseases, a more holistic approach is necessary to mitigate or control them in low-income nations.

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