01219nas a2200217   4500000000100000008004100001653000900042653002000051653004000071100001200111700001400123700001400137700001300151700002200164245007200186856009800258300001300356490000700369520061100376022001400987       2017                            d10aNTDs10aTrypanosomiasis10aHuman African Trypanosomiasis (HAT)1 aAksoy S1 aBuscher P1 aLehane MJ1 aSolano P1 aVan Den Abbeele J00aHuman African trypanosomiasis control: Achievements and challenges.  uhttp://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0005454&type=printable  ae00054540 v113 a<p>Sleeping sickness, also known as human African trypanosomiasis (HAT), is a neglected disease that impacts 70 million people living in 1.55 million km2 in sub-Saharan Africa. Since the beginning of the 20th century, there have been multiple HAT epidemics in sub-Saharan Africa, with the most recent epidemic in the 1990s resulting in about half a million HAT cases reported between 1990 and 2015. Here we review the status of HAT disease at the current time and the toolbox available for its control. We also highlight future opportunities under development towards novel or improved interventions.</p>
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