01388nas a2200205   4500000000100000008004100001653001700042653001500059653001400074653001500088653001300103653001200116100001400128700001400142245006500156856005900221300001200280490000600292520088400298       2016                            d10aTransmission10aPrevention10aNeglected10aHost range10aHookworm10aBiology1 aHossain M1 aBhuiyan J00aHookworm infection: A neglected tropical disease of mankind.  uhttp://www.ejmanager.com/mnstemps/39/39-1460626363.pdf  a297-3200 v33 a<p>Hookworm infection, a global problem of human, is caused by both <em>Ancylostoma duodenale </em>and <em>Necator americanus</em>. These parasites are considered as important blood feeding nematodes. Hookworm is usually prevalent among the people who live with low socio-economic status. However, this tropical disease is neglected in most cases. This review was aimed at investigating the insights of hookworm infection of human considering its epidemiology, pathogenesis, clinical manifestation, diagnosis, treatment, immune mechanism, prevention, and control. This study showed how hookworm infection poses a global burden and infects 438.9 million people around the word annualy, and causes significant morbidity among the children and adult in endemic countries. Also, this review discussed how hookworm infection threatens the mankind causing serious health hazards.</p>