02847nas a2200217   4500000000100000008004100001653002000042653002600062653001600088653001000104100001100114700001200125700001100137700001200148245012900160856026000289300000700549490000600556520205300562022001402615       2016                            d10aschistosomiasis10aSchistosoma japonicum10aElimination10aChina1 aZhou Y1 aLiang S1 aChen Y1 aJiang Q00aThe Three Gorges Dam: Does it accelerate or delay the progress towards eliminating transmission of schistosomiasis in China?  uhttp://download.springer.com/static/pdf/205/art%253A10.1186%252Fs40249-016-0156-3.pdf?originUrl=http%3A%2F%2Fidpjournal.biomedcentral.com%2Farticle%2F10.1186%2Fs40249-016-0156-3&token2=exp=1467803442~acl=%2Fstatic%2Fpdf%2F205%2Fart%25253A10.1186%25252Fs40  a630 v53 a<p>The Three Gorges Dam, located in the largest endemic area of schistosomiasis in China, is one of the world's largest hydroelectric projects to date. Some large-scale hydro projects have resulted in schistosomiasis emergence or re-emergence. Therefore, the dam's potential impact on the transmission of Schistosoma japonicum has raised concerns from medical researchers worldwide. A systematic literature review, coupled with an analysis of data on the water level and snail density in the Yangtze River was conducted to assess the impact of the dam on schistosomiasis transmission after more than 10&nbsp;years of operation. The dam has significantly altered the water levels in the Yangtze River according to different seasons. These changes directly impact the ecology of the schistosome snail host. Due to the dam, there has been a reduction in the density of Oncomelania snails and/or changes in the distribution of snails. The prevalence of infection with S. japonicum has decreased in the downstream areas of the dam, including in the Dongting and Poyang Lakes. The prevalence of infection with S. japonicum in humans has decreased from 6.80&nbsp;% in 2002 (before the dam began operating) to 0.50&nbsp;% in 2012, and the number of people infected with S. japonicum have decreased from 94 208 in 2002 to 59 200 in 2011 in the Poyang Lake region. The presence of the dam does not seem to affect snail breeding or the prevalence of schistosomiasis in the Three Gorges Reservoir. Overall, the Three Gorges Dam has significantly contributed to changes in hydrology after more than 10&nbsp;years of the dam operating. The changes caused by the dam, together with integrated control of schistosomiasis, might be accelerating the progress towards eliminating the transmission of S. japonicum in the middle and lower reaches of the Yangtze River. Despite the positive effect the dam is having in controlling S. japonicum transmission, continued surveillance is required to monitor the future ecological impacts of the dam over the long term.</p>
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