01836nas a2200181   4500000000100000008004100001653001000042653001900052653003900071653001200110653002200122100001800144700001200162700001300174245009700187520135600284022001401640       2016                            d10aYemen10aonchocerciasis10aNeglected tropical diseases (NTDs)10aMapping10aControl programme1 aAbdul-Ghani R1 aMahdy M1 aBeier JC00aOnchocerciasis in Yemen: Time to take action against a neglected tropical parasitic disease.3 a<p>Onchocerciasis is a neglected parasitic disease affecting the poorest underserved people in Yemen. A national control programme with goals to eliminate onchocerciasis has yet to be launched due to the current upheaval and social unrest in the country. The disease locally termed sowda is unique in its clinicopathologic pattern, being of the localized, non-blinding, hyperreactive onchocercal skin disease. Although early reports identified endemic foci along seasonal watercourses, there is a need to redefine epidemiologic patterns as well as health and socioeconomic impacts. Laboratory diagnosis of sowda among Yemeni patients is difficult due to the light load of microfilariae in skin snips and the presence of asymptomatic itching-free microfilaria carriers. Adoption of ivermectin use at three-month intervals as a control strategy has not been evaluated because the drug is mostly used in clinics and distributed to only a few affected communities. This paper addresses key aspects of onchocerciasis in Yemen and highlights the need for screening at-risk populations using highly sensitive techniques and mapping the distributions of the parasite in human and vector populations of blackflies. The new research should be integrated with the launch of a national onchocerciasis control programme to achieve onchocerciasis elimination.</p>
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