02945nas a2200301   4500000000100000008004100001653002400042653003900066653001600105653001200121653001000133100001200143700000900155700001100164700001100175700000900186700001700195700001000212700001500222700001300237700001100250245008000261856007900341300000700420490000600427520219600433022001402629       2014                            d10aSurveillance system10aNeglected tropical diseases (NTDs)10aElimination10aControl10aChina1 aTambo E1 aAi L1 aZhou X1 aChen J1 aHu W1 aBergquist RN1 aGuo J1 aUtzinger J1 aTanner M1 aZhou X00aSurveillance-response systems: the key to elimination of tropical diseases.  uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071800/pdf/2049-9957-3-17.pdf  a170 v33 a<p>Tropical diseases remain a major cause of morbidity and mortality in developing countries. Although combined health efforts brought about significant improvements over the past 20 years, communities in resource-constrained settings lack the means of strengthening their environment in directions that would provide less favourable conditions for pathogens. Still, the impact of infectious diseases is declining worldwide along with progress made regarding responses to basic health problems and improving health services delivery to the most vulnerable populations. The London Declaration on Neglected Tropical Diseases (NTDs), initiated by the World Health Organization's NTD roadmap, set out the path towards control and eventual elimination of several tropical diseases by 2020, providing an impetus for local and regional disease elimination programmes. Tropical diseases are often patchy and erratic, and there are differing priorities in resources-limited and endemic countries at various levels of their public health systems. In order to identify and prioritize strategic research on elimination of tropical diseases, the 'First Forum on Surveillance-Response System Leading to Tropical Diseases Elimination' was convened in Shanghai in June 2012. Current strategies and the NTD roadmap were reviewed, followed by discussions on how to identify and critically examine prevailing challenges and opportunities, including inter-sectoral collaboration and approaches for elimination of several infectious, tropical diseases. A priority research agenda within a 'One Health-One World' frame of global health was developed, including (i) the establishment of a platform for resource-sharing and effective surveillance-response systems for Asia Pacific and Africa with an initial focus on elimination of lymphatic filariasis, malaria and schistosomiasis; (ii) development of new strategies, tools and approaches, such as improved diagnostics and antimalarial therapies; (iii) rigorous validation of surveillance-response systems; and (iv) designing pilot studies to transfer Chinese experiences of successful surveillance-response systems to endemic countries with limited resources.</p>  a2049-9957