02770nas a2200241   4500000000100000008004100001653001300042653001500055653001200070653003900082653002900121653001200150100001400162700001500176700001600191700001700207245009000224856007700314300001000391490000600401520210700407022001402514       2014                            d10aResearch10aPrevention10aNigeria10aNeglected tropical diseases (NTDs)10aMass drug administration10aControl1 aOkorie PN1 aBockarie M1 aMolyneux DH1 aKelly-Hope L00aNeglected tropical diseases: a systematic evaluation of research capacity in Nigeria.  uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133230/pdf/pntd.0003078.pdf  ae30780 v83 a<p><b>BACKGROUND: </b>Nigeria carries the highest burden and diversity of neglected tropical diseases (NTDs) in sub-Saharan Africa and is preparing to scale up its efforts to control/eliminate these diseases. To achieve this it will require a range of internal technical support and expertise for mapping, monitoring and evaluating, operational research and documenting its success. In order to begin to evaluate this potential in Nigeria, this study collated and analysed information for lymphatic filariasis (LF), onchocerciasis, schistosomiasis and soil-transmitted helminths (STH), which are currently being targeted with preventive chemotherapy through mass drug administration (MDA).</p><p><b>METHODOLOGY/PRINCIPAL FINDINGS: </b>Information from 299 scientific articles published on the selected NTDs in 179 journals between January 2008 and September 2013 was extracted and systematically compiled into a geo-referenced database for analysis and mapping. The highest number of articles was from the southern geo-political zones of the country. The majority of articles focused on one specific disease, and schistosomiasis and STH were found to have the highest and most wide ranging research output. The main type of study was parasitological, and the least was biotechnological. Nigerian authors were mostly affiliated with universities, and there was a wide range of international co-authors from Africa and other regions, especially the USA and UK. The majority of articles were published in journals with no known impact factor.</p><p><b>CONCLUSIONS/SIGNIFICANCE: </b>The extensive database and series of maps on the research capacity within Nigeria produced in this study highlights the current potential that exists, and needs to be fully maximized for the control/elimination of NTDs in the country. This study provides an important model approach that can be applied to other low and middle income countries where NTDs are endemic, and NTD programmes require support from the expertise within their own country, as well as internationally, to help raise their profile and importance.</p>  a1935-2735