01791nas a2200313   4500000000100000008004100001260001200042653001400054653001700068653001400085653002700099653001300126653001200139653001700151653004000168100001600208700001500224700001300239700001000252700001300262700001500275700001500290245006800305856007000373300001200443490000700455520100100462022001401463       2025                            d  c03/202510aAustralia10aBuruli ulcer10aMelbourne10aMycobacterium ulcerans10aBacteria10aendemic10aEpidemiology10aTuberculosis and other mycobacteria1 aRavindran B1 aHennessy D1 aO'Hara M1 aTay E1 aBanuve R1 aMcVernon J1 aCarville K00aEpidemiology of Buruli Ulcer in Victoria, Australia, 2017-2022.  uhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11878321/pdf/24-0938.pdf  a448-4570 v313 a<p>Buruli ulcer (BU) is a rare, neglected tropical disease caused by Mycobacterium ulcerans that can lead to severe skin ulcers. To determine the epidemiology of BU in Victoria, Australia, during 2017-2022 we analyzed surveillance data. A total of 1,751 cases of BU were notified; 968 (55%) patients were male and 781 (45%) female (2 were missing sex data), and 984 (56%) resided in established BU-endemic areas, although an increasing number were in new BU-endemic areas. Most cases (83%, 1,301) were classified as category I. Multivariate modeling demonstrated that factors for severe BU included being male, being older, and living in a new BU-endemic or non-BU-endemic area. A relatively shorter interval between first visit to a clinician and receipt of diagnosis was protective against severe disease. The expansion of BU-endemic areas throughout Victoria remains a public health concern and calls for targeted action, particularly for patients and clinicians in new BU-endemic areas.</p>
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