02793nas a2200265   4500000000100000008004100001653001200042653001500054653001900069653002900088653001900117653001400136100002100150700001700171700001200188700001200200700000800212700000900220700001500229700001300244245013000257856026000387300001200647520186800659       2024                            d10aLeprosy10aDermoscopy10aHistopathology10a Granulomatous Disorders10aHistoid Hansen10aReactions1 aChenganasseri SH1 aKapilavayi S1 aDivya B1 aPanat M1 aD I1 aSK M1 aKrishna AV1 aSingh TR00aCorrelation of Dermatoscopic Findings in Leprosy with Clinical Spectrum and Histopathology: A Prospective Observational Study  uhttps://scholar.google.nl/scholar_url?url=https://www.ijl.org.in/published-articles/16092024125309/4_original_article_Sameeha_HC_et_al_print_version.pdf&hl=nl&sa=X&d=12044586246020434284&ei=lLPzZr7WDY7Zy9YP4IS1-QI&scisig=AFWwaeYB3YUtMCFb6oqsTQs4Bgou&oi=sc  a215-2303 a<p>The variety of clinical presentations makes leprosy a diagnostic challenge and it must be differentiated from other granulomatous dermatoses. Dermoscopy is a handy tool that can aid in its diagnosis. This study has been carried out to evaluate the dermoscopic findings in different spectrums of leprosy and its reactions and to correlate it with the clinical and histopathological findings. This was a prospective observational study of treatment naïve leprosy patients carried out over a period of 6 months. The study patients were categorized as per Ridley-Jopling classification. Dermoscopy and biopsy of every patient were carried out. A total of 50 patients were recruited in this study. The most common type of leprosy found was Lepromatous Leprosy (30%), followed by Borderline Tuberculoid leprosy (22%). Type 1 lepra reaction was noted in 13 patients, whereas 12 patients exhibited type 2 lepra reactions. White and yellowish brown structureless areas histologically corresponding to dermal granulomas, whereas chrysalis-like streaks and variable loss of appendageal structures, corresponding to dermal fibrosis and peri appendageal granulomas, respectively were the predominant features. Scaling, yellowish brown structureless areas, reduced pigmentary network were more commonly seen towards tuberculoid pole whereas accentuation of reticular pigment and chrysalis like streaks towards the lepromatous pole. Erythema, dilated blood vessels were seen in patients in reaction meanwhile follicular plugging and scaling were observed in type 1 reaction. Other unique findings included targetoid pattern and petal like arrangement in type 2 reaction and Histoid Hansens, respectively. The data showed an excellent correlation between histology and dermoscopic findings. Dermoscopy is a non-invasive tool that can complement histopathological tests.</p>