01927nas a2200265   4500000000100000008004100001260001200042653001300054653002500067653001200092653001800104653002400122653003200146653001500178653002000193100001300213700001400226700001400240245006900254856007100323300000800394490000700402520123800409022001401647       2024                            d  c12/202410aCovid-1910aDeveloping countries10aFunding10aGlobal health10aInfectious Diseases10aNeglected Tropical Diseases10aOne Health10aTrypanosomiasis1 aKasozi K1 aMacLeod E1 aWelburn S00aOne Health policy for combatting African trypanocide resistance.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367463/pdf/main.pdf  a1-50 v193 a<p>The rise of African trypanocide resistance (ATr) is influenced by various factors such as evolutionary changes in the pathogen, the presence of resistance genes in the population, poor policy decisions, limited private-public partnerships to engage local communities, and insufficient funding for the development of new drugs over the past sixty years. These challenges have been exacerbated by the inadequate implementation of drug liberalization policies in the mid 20th century, leading to poor pharmacovigilance practices for veterinary drugs in low and middle income countries (LMICs). One health (OH), a disease management framework, provides practical solutions for addressing ATr, drawing on its success in managing previous epidemics like avian influenza in 2004 and the recent COVID-19 pandemic, where institutional collaborations were rapidly established. To combat ATr, OH initiatives involving both international and local partners at the policy and grassroots levels are crucial to generate community interest. The importance of political commitment, media involvement, and nongovernmental organizations cannot be overstated, as they are essential for resource mobilization and long-term sustainability in LMICs.</p>  a2352-7714