@article{98191,
  keywords = {Infectious Diseases, Microbiology (medical), Epidemiology, Chromoblastomycosis, Madagascar},
  author = {Rasamoelina T and Maubon D and Andrianarison M and Ranaivo I and Sendrasoa F and Rakotozandrindrainy N and Rakotomalala FA and Bailly S and Rakotonirina B and Andriantsimahavandy A and Rabenja FR and Andrianarivelo MR and Cornet M and Ramarozatovo LS},
  title = {Endemic Chromoblastomycosis Caused Predominantly by <i>Fonsecaea nubica</i>, Madagascar1},
  abstract = {<p>Chromoblastomycosis is an implantation fungal infection. Twenty years ago, Madagascar was recognized as the leading focus of this disease. We recruited patients in Madagascar who had chronic subcutaneous lesions suggestive of dermatomycosis during March 2013–June 2017. Chromoblastomycosis was diagnosed in 50 (33.8%) of 148 patients. The highest prevalence was in northeastern (1.47 cases/100,000 persons) and southern (0.8 cases/100,000 persons) Madagascar. Patients with chromoblastomycosis were older (47.9 years) than those without (37.5 years) (p = 0.0005). Chromoblastomycosis was 3 times more likely to consist of leg lesions (p = 0.003). Molecular analysis identified&nbsp;<em>Fonsecaea nubica</em>&nbsp;in 23 cases and&nbsp;<em>Cladophialophora carrionii</em>&nbsp;in 7 cases. Of 27 patients who underwent follow-up testing, none were completely cured. We highlight the persistence of a high level of chromoblastomycosis endemicity, which was even greater at some locations than 20 years ago. We used molecular tools to identify the&nbsp;<em>Fonsecaea</em>&nbsp;sp. strains isolated from patients as&nbsp;<em>F. nubica</em>.</p>
},
  year = {2020},
  journal = {Emerging Infectious Diseases},
  volume = {26},
  pages = {1201-1211},
  publisher = {Centers for Disease Control and Prevention (CDC)},
  issn = {1080-6040, 1080-6059},
  url = {https://wwwnc.cdc.gov/eid/article/26/6/pdfs/19-1498.pdf},
  doi = {10.3201/eid2606.191498},
  language = {Eng},
}