@inbook{33336,
  keywords = {Neglected tropical diseases (NDTs), Public health, Control programmes, mass drug administration (MDA), preventative chemotherapy, Lymphatic filariasis (LF), onchocerciasis, schistosomiasis, Soil-transmitted helminth (STH), Trachoma, Yaws},
  author = {Hotez P J and Lo NC},
  title = {Chapter 27 Neglected Tropical Diseases: Public Health Control Programs and Mass Drug Administration},
  abstract = {<p>A principle approach to the control of some of the major&nbsp;<a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/neglected-tropical-diseases" style="box-sizing: border-box; margin: 0px; padding: 0px; background-color: transparent; text-decoration-line: none; color: rgb(12, 125, 187); word-break: break-word;" title="Learn more about Neglected Tropical Diseases from ScienceDirect's AI-generated Topic Pages">neglected tropical diseases</a>(NTDs), including&nbsp;<a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/lymphatic-filariasis" style="box-sizing: border-box; margin: 0px; padding: 0px; background-color: transparent; text-decoration-line: none; color: rgb(12, 125, 187); word-break: break-word;" title="Learn more about Lymphatic Filariasis from ScienceDirect's AI-generated Topic Pages">lymphatic filariasis</a>&nbsp;(LF),&nbsp;<a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/onchocerciasis" style="box-sizing: border-box; margin: 0px; padding: 0px; background-color: transparent; text-decoration-line: none; color: rgb(12, 125, 187); word-break: break-word;" title="Learn more about Onchocerciasis from ScienceDirect's AI-generated Topic Pages">onchocerciasis</a>,&nbsp;<a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/schistosomiasis" style="box-sizing: border-box; margin: 0px; padding: 0px; background-color: transparent; text-decoration-line: none; color: rgb(12, 125, 187); word-break: break-word;" title="Learn more about Schistosomiasis from ScienceDirect's AI-generated Topic Pages">schistosomiasis</a>, soil-transmitted&nbsp;<a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/helminthiasis" style="box-sizing: border-box; margin: 0px; padding: 0px; background-color: transparent; text-decoration-line: none; color: rgb(12, 125, 187); word-break: break-word;" title="Learn more about Helminthiasis from ScienceDirect's AI-generated Topic Pages">helminth infections</a>,&nbsp;<a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/trachoma" style="box-sizing: border-box; margin: 0px; padding: 0px; background-color: transparent; text-decoration-line: none; color: rgb(12, 125, 187); word-break: break-word;" title="Learn more about Trachoma from ScienceDirect's AI-generated Topic Pages">trachoma</a>, and&nbsp;<a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/yaws" style="box-sizing: border-box; margin: 0px; padding: 0px; background-color: transparent; text-decoration-line: none; color: rgb(12, 125, 187); word-break: break-word;" title="Learn more about Yaws from ScienceDirect's AI-generated Topic Pages">yaws</a>, has relied on mass treatment of populations at risk for these infections, together with key donations of essential NTD medicines from multinational pharmaceutical companies. Known as&nbsp;<em>mass drug administration (MDA)</em>&nbsp;or&nbsp;<em>preventive chemotherapy,</em>&nbsp;this approach is now yielding important public health gains. Beginning in 2006 access to essential NTD medicines in resource-poor nations was accelerated through integration of MDA programs (by combining these medicines in a package of interventions), along with expanded financial support from the governments of the United States and United Kingdom, and coordination by the World Health Organization. As a result we have seen dramatic reductions in the global prevalence of LF, onchocerciasis, and trachoma, and as such some of these NTDs could be eliminated in the coming decade, whereas for soil-transmitted helminth infections or schistosomiasis we may need to revise current approaches or introduce improved control tools. Still for other NTDs, including the major kinetoplastid infections, intensified disease management through case detection, treatment, and&nbsp;<a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/vector-control" style="box-sizing: border-box; margin: 0px; padding: 0px; background-color: transparent; text-decoration-line: none; color: rgb(12, 125, 187); word-break: break-word;" title="Learn more about Vector Control from ScienceDirect's AI-generated Topic Pages">vector control</a>&nbsp;will be required. Better drugs or new vaccines will also be needed for optimal control for many of the NTDs.</p>
},
  year = {2020},
  journal = {Hunter's Tropical Medicine and Emerging Infectious Diseases},
  edition = {10th},
  chapter = {27},
  pages = {209-213},
  publisher = {Elsevier},
  isbn = {978-0-323-55512-8},
  url = {https://www.sciencedirect.com/science/article/pii/B9780323555128000272},
  language = {eng},
}