@article{28541, keywords = {Trachoma, Odds Ratio, Logistic Models, Infant, Humans, Ethiopia, Communicable Disease Control, Child, Preschool, Azithromycin, Anti-Bacterial Agents}, author = {Chidambaram J and Melese M and Alemayehu W and Yi E and Prabriputaloong T and Lee DC and Cevallos V and Zhou Z and Whitcher J and Gaynor B and Lietman TM}, title = {Mass antibiotic treatment and community protection in trachoma control programs.}, abstract = {
Azithromycin is highly effective against trachoma, but the practical difficulties of community-wide distribution often leave many individuals untreated. We demonstrate, after mass azithromycin treatment of a population in Ethiopia, an indirect protective effect that occurred among untreated children who resided in villages in which most individuals had been treated. Similarities with the indirect protection within a treated community (i.e., "herd protection") that has been observed in vaccination programs are discussed.
}, year = {2004}, journal = {Clinical infectious diseases : an official publication of the Infectious Diseases Society of America}, volume = {39}, pages = {e95-7}, issn = {1537-6591}, url = {http://cid.oxfordjournals.org/content/39/9/e95.full.pdf+html}, doi = {10.1086/424747}, language = {eng}, }