@article{27768,
  keywords = {Time trend analysis, Spatial analysis, Negelected Tropical Diseases, Mortality, Epidemiology, Brazil},
  author = {Martins-Melo FR and Novaes Ramos A and Alencar C and Heukelbach J},
  title = {Trends and spatial patterns of mortality related to neglected tropical diseases in Brazil.},
  abstract = {<p>We analysed nationwide trends and spatial distribution of NTD-related mortality in Brazil. We included all death certificates in Brazil from 2000 to 2011, in which NTDs were recorded as any causes of death. A total of 100,814/12,491,280 (0.81%) death certificates were identified, which mentioned at least one NTD. Age-adjusted NTD-related mortality rates showed a significant decrease over time (annual percent change [APC]: −2.1%; 95% CI: −2.8 to −1.3), with decreasing mortality rates in the Southeast, South, and Central-West regions, stability in the Northeast region, and increase in the North region. We identified spatial and spatiotemporal high-risk clusters for NTD-related mortality in all regions, with a major cluster covering a wide geographic range in central Brazil. Despite nationwide decrease of NTD-related mortality in the observation period, regional differences remain, with increasing mortality trends especially in the socioeconomically disadvantaged regions of the country. The existence of clearly defined high-risk areas for NTD-related deaths reinforces the need for integrated prevention and control measures in areas with highest disease burden.</p>
},
  year = {2016},
  journal = {Parasite Epidemiology and Control},
  volume = {1},
  pages = {56-65},
  issn = {24056731},
  url = {https://www.researchgate.net/profile/Alberto_Ramos_Jr/publication/299845110_Trends_and_spatial_patterns_of_mortality_related_to_neglected_tropical_diseases_in_Brazil/links/570629b508ae44d70ee352a2.pdf},
  doi = {10.1016/j.parepi.2016.03.002},
  language = {eng},
}